A while ago a bug on GTK that cased direction of applications without translation to right to left (no translation = not necessary to change direction) was fixed.
http://bugzilla.gnome.org/show_bug.cgi?id=503071
If i understated correctly, wxwidgets on Linux distro's is actually a wrapper around GTK,
and is looks like wxwidgets was not affected by this fix.
Example: http://ilsh.info/wp-content/uploads/2009/05/hebsup4.png
i am not sure it's a wxwidgets bug, i'll ask here first anyway.